Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cbiLPrecorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. (242 aa)    
Predicted Functional Partners:
cbiJ
precorrin-3B C17-methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG1010.
  
 0.999
cbiC
precorrin-8X methylmutase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2082.
 
  
 0.996
cbiF
Precorrin-4 C11-methyltransferase protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2875; Belongs to the precorrin methyltransferase family.
 
  
 0.995
cbiG
Precorrin methylase protein; Identified by sequence similarity; putative; ORF located using Blastx/COG2073.
 
  
 0.994
cbiD
Cobalamin biosynthesis cbiD transmembrane protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.990
cobA1
uroporphyrin-III C-methyltransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0007; Belongs to the precorrin methyltransferase family.
 
 
 0.977
cobL
precorrin-6Y methylase methyltransferase protein; Identified by sequence similarity; putative; ORF located using Blastx/COG2241.
 
  
 0.976
cobQ
Cobyric acid synthase protein; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.976
cobA2
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
  
 0.960
cobN
Cobalamin biosynthesis protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1429.
 
  
 0.926
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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