Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
norMProbable transmembrane efflux protein / multidrug resistance protein; Multidrug efflux pump; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. (465 aa)    
Predicted Functional Partners:
murB
UDP-N-acetylmuramate dehydrogenase; Cell wall formation.
 
     0.836
lytB
lytB protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
     
 0.731
rpsA
30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
  
    0.722
CV_0190
Probable glyceraldehyde 3-phosphate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
  
 0.686
gapA
Glyceraldehyde-3-phosphate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
  
 0.686
CV_2450
Hypothetical protein.
   
  
 0.682
CV_2978
Probable geranylgeranyl-diphosphate geranylgeranyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/COG1562.
   
  
 0.682
CV_2979
Probable phytoene synthase-related protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1562.
   
  
 0.682
rplO
50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
    
   0.667
mucD
Serine protease MucD precursor; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0265; Belongs to the peptidase S1C family.
   
  
 0.652
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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