Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
acrEProbable RND efflux membrane fusion protein precursor; identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0845/TC:8.A.1.6.1; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (368 aa)    
Predicted Functional Partners:
CV_1626
Probable multidrug efflux protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0841/TC:2.A.6.2.2; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.993
natC
Periplasmic type I secretion system; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1538/TC:1.B.17.1.1.
  
 0.949
acrD
Acriflavin resistance protein D; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0841/TC:2.A.6.2.7.
 
 0.928
nolG
NolG efflux transporter; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0841/TC:2.A.6.2.12; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.925
CV_3836
Probable multidrug efflux membrane protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0841/TC:2.A.6.1.2; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.923
acrB
Acriflavin resistance protein B; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0841/TC:2.A.6.2.2.
 
 0.920
macB
Probable ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.902
CV_1628
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1538.
 
 
 0.847
CV_1734
Probable outer membrane protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1538/TC:1.B.17.2.1.
 
 0.751
CV_2734
Probable drug efflux pump transmembrane protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0841/TC:2.A.6.2.12; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.719
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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