Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
desDlinoleoyl-CoA desaturase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG3239. (369 aa)    
Predicted Functional Partners:
CV_2452
Probable linoleoyl-CoA desaturase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG3239.
  
  
 
0.925
dnaJ
Heat shock protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
     
 0.766
nadR
Nicotinamide mononucleotide-binding domain; Identified by sequence similarity; putative; ORF located using Blastx/COG3172.
  
     0.686
vioC
vioC monooxygenase; Catalyzes the hydroxylation of the 16-position of protoviolaceinate and protodeoxyviolaceinate to form violacein and deoxyviolacein, respectively.
  
  
 0.657
holA
DNA-directed DNA polymerase, delta subunit; Identified by sequence similarity; putative; ORF located using Blastx/COG1466.
      
 0.619
CV_4372
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG3000.
 
  
 0.567
dnaK
Heat shock protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
     
 0.510
CV_1774
Probable flavohemoprotein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1018.
  
  
 0.482
hemF
Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
  
     0.475
CV_1020
Probable DNA-directed DNA polymerase III (epsilon subunit); Identified by sequence similarity; putative; ORF located using Blastx/COG0847.
 
     0.438
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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