Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hcnCHydrogen cyanide synthase HcnC; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0665. (419 aa)    
Predicted Functional Partners:
hcnB
Hydrogen cyanide synthase HcnB; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0446.
 
 0.999
hcnA
Hydrogen cyanide synthase HcnA; Identified by sequence similarity; putative; ORF located using Blastx/COG0446.
    
 0.991
thiG
Thiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 0.967
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.917
pepA
Aminopeptidase A/I; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
    
 0.814
gshB
Glutathione synthetase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0189.
     
 0.809
pepN
Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0308.
     
  0.800
pepD
Aminoacyl-histidine dipeptidase precursor; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2195.
     
  0.800
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.672
CV_2826
Probable proline racemace; Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Can also catalyze the epimerization of trans-3-hydroxy-L-proline (t3LHyp) to cis-3-hydroxy-D-proline (c3DHyp), albeit with 19-fold lower efficiency. Displays no proline racemase activity.
 
   
 0.657
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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