Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hcnBHydrogen cyanide synthase HcnB; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0446. (468 aa)    
Predicted Functional Partners:
hcnC
Hydrogen cyanide synthase HcnC; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0665.
 
 0.999
hcnA
Hydrogen cyanide synthase HcnA; Identified by sequence similarity; putative; ORF located using Blastx/COG0446.
    
 0.988
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.935
CV_0081
Probable cytochrome c4; Identified by sequence similarity; putative; ORF located using Blastx/COG2863.
   
 
 0.847
CV_1816
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG2146.
  
 
 0.847
cyc
Cytochrome-c oxidase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2863.
   
 
 0.847
pepD
Aminoacyl-histidine dipeptidase precursor; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2195.
   
 
 0.811
pepN
Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0308.
     
  0.800
pepA
Aminopeptidase A/I; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
  0.800
gshB
Glutathione synthetase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0189.
     
  0.800
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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