| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CV_0081 | hcnB | CV_0081 | CV_1683 | Probable cytochrome c4; Identified by sequence similarity; putative; ORF located using Blastx/COG2863. | Hydrogen cyanide synthase HcnB; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0446. | 0.847 |
| CV_1816 | hcnB | CV_1816 | CV_1683 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG2146. | Hydrogen cyanide synthase HcnB; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0446. | 0.847 |
| cyc | hcnB | CV_4386 | CV_1683 | Cytochrome-c oxidase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2863. | Hydrogen cyanide synthase HcnB; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0446. | 0.847 |
| glyA | gshB | CV_1286 | CV_4275 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glutathione synthetase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0189. | 0.829 |
| glyA | hcnA | CV_1286 | CV_1684 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hydrogen cyanide synthase HcnA; Identified by sequence similarity; putative; ORF located using Blastx/COG0446. | 0.923 |
| glyA | hcnB | CV_1286 | CV_1683 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hydrogen cyanide synthase HcnB; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0446. | 0.935 |
| glyA | hcnC | CV_1286 | CV_1682 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hydrogen cyanide synthase HcnC; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0665. | 0.917 |
| glyA | pepA | CV_1286 | CV_2914 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aminopeptidase A/I; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.848 |
| glyA | pepD | CV_1286 | CV_2694 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aminoacyl-histidine dipeptidase precursor; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2195. | 0.915 |
| glyA | pepN | CV_1286 | CV_1176 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0308. | 0.873 |
| gshB | glyA | CV_4275 | CV_1286 | Glutathione synthetase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0189. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.829 |
| gshB | hcnA | CV_4275 | CV_1684 | Glutathione synthetase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0189. | Hydrogen cyanide synthase HcnA; Identified by sequence similarity; putative; ORF located using Blastx/COG0446. | 0.800 |
| gshB | hcnB | CV_4275 | CV_1683 | Glutathione synthetase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0189. | Hydrogen cyanide synthase HcnB; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0446. | 0.800 |
| gshB | hcnC | CV_4275 | CV_1682 | Glutathione synthetase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0189. | Hydrogen cyanide synthase HcnC; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0665. | 0.809 |
| gshB | pepA | CV_4275 | CV_2914 | Glutathione synthetase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0189. | Aminopeptidase A/I; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.939 |
| gshB | pepD | CV_4275 | CV_2694 | Glutathione synthetase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0189. | Aminoacyl-histidine dipeptidase precursor; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2195. | 0.923 |
| gshB | pepN | CV_4275 | CV_1176 | Glutathione synthetase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0189. | Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0308. | 0.926 |
| hcnA | glyA | CV_1684 | CV_1286 | Hydrogen cyanide synthase HcnA; Identified by sequence similarity; putative; ORF located using Blastx/COG0446. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.923 |
| hcnA | gshB | CV_1684 | CV_4275 | Hydrogen cyanide synthase HcnA; Identified by sequence similarity; putative; ORF located using Blastx/COG0446. | Glutathione synthetase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0189. | 0.800 |
| hcnA | hcnB | CV_1684 | CV_1683 | Hydrogen cyanide synthase HcnA; Identified by sequence similarity; putative; ORF located using Blastx/COG0446. | Hydrogen cyanide synthase HcnB; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0446. | 0.988 |