Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CV_1806Probable hydroxymethylglutaryl-CoA reductase (NADPH2); Identified by sequence similarity; putative; ORF located using Blastx/COG1257. (361 aa)    
Predicted Functional Partners:
CV_1807
Probable biotin carboxylase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0439.
       0.773
CV_1808
Hypothetical protein.
       0.752
pncA
Bifunctional pyrazinamidase/nicotinamidase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1335.
 
      0.730
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 
    0.563
idsA
Bifunctional short chain isoprenyl diphosphate; Identified by sequence similarity; putative; ORF located using Blastx/COG0142; Belongs to the FPP/GGPP synthase family.
 
 
 0.545
CV_1809
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG2079.
       0.484
ubiF
Monooxygenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0654.
   
  
 0.481
CV_1403
Probable secreted protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0654.
   
  
 0.481
CV_1826
Probable FAD-dependent monooxygenase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0654.
   
  
 0.481
visC
Oxidoreductase protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0654.
   
  
 0.481
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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