Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CV_1807Probable biotin carboxylase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0439. (496 aa)    
Predicted Functional Partners:
mmdA
Acetyl-CoA carboxylase alpha subunit; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0825.
 
 0.994
CV_0019
Probable propionyl CoA carboxylase, beta subunit; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0825/TC:3.B.1.1.2.
 
 0.988
CV_1764
Probable propionyl-CoA carboxylase (beta subunit); Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0825/TC:3.B.1.1.2.
 
 0.984
accD
acetyl-CoA carboxylase (carboxyl transferase subunit beta); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 0.977
accA
acetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
 
 0.933
CV_1808
Hypothetical protein.
 
 
 0.922
accB
acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.849
mvaB
hydroxymethylglutaryl-CoA lyase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0119/TC:3.B.1.1.1.
  
  
 0.809
birA
Biotin acetyl-CoA-carboxylase synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
  
 0.799
aceF
Dihydrolipoamide S-acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.776
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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