Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sohBSerine protease; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0616. (312 aa)    
Predicted Functional Partners:
motB1
Chemotaxis motB protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1360/TC:1.A.30.1.2.
     
 0.785
CV_1813
Probable nitroreductase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0778.
     
 0.749
CV_1816
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG2146.
 
     0.724
CV_1817
Probable phosphoglycolate phosphatase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0546.
  
  
 0.709
rluC
Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
  
    0.707
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
       0.554
slyB
PAL cross-reacting lipoprotein precursor; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3133.
       0.507
yidC
Integral membrane protein, 60 kDa; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
  
 0.430
CV_0448
Probable ABC transport system permease protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0767.
 
     0.426
topA
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
     
 0.426
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.