Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cynSCyanate lyase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family. (155 aa)    
Predicted Functional Partners:
cynT
Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
 
 
 0.990
CV_0520
Probable carbonate dehydratase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0288.
  
 
 0.926
arcC
Carbamate kinase; Identified by sequence similarity; putative; ORF located using Blastx/COG0549; Belongs to the carbamate kinase family.
     
  0.900
cynR
Cyn operon transcriptional regulator; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG0583; Belongs to the LysR transcriptional regulatory family.
 
   
 0.823
CV_1136
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0288/TC:2.C.1.2.1.
  
 
 0.638
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
     
 0.574
CV_4309
Probable L-allo-threonine aldolase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2008.
      
 0.574
cioA
Cyanide insensitive terminal oxidase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1271.
      
 0.543
hisC
Histidinol-phosphate aminotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0079; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
      
 0.529
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
      
 0.525
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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