Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CV_1987Probable metallopeptidase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3590. (667 aa)    
Predicted Functional Partners:
polA
DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.567
exbD4
Biopolymer transport exbD transmembrane protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0848.
       0.559
exbB2
Biopolymer transport protein; Identified by sequence similarity; putative.
       0.548
exbD1
Biopolymer transport exbD transmembrane protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0848.
       0.548
CV_1982
Probable tonB dependent receptor; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1629/TC:1.B.14.3.1.
 
     0.513
ruvB
Holliday junction DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
   
    0.513
CV_0311
Probable RTX (repeat in structural toxin); Identified by sequence similarity; putative; ORF located using Blastx/COG2931.
  
    0.466
CV_0464
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx.
  
    0.466
CV_0516
Probable calcium binding hemolysin; Identified by sequence similarity; putative; ORF located using Blastx/COG2931/TC:1.C.11.1.4.
  
    0.466
CV_1737
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx.
  
    0.466
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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