Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gphPhosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (222 aa)    
Predicted Functional Partners:
rpe
Ribulose-phosphate 3-epimerase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0036; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.969
CV_1817
Probable phosphoglycolate phosphatase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0546.
  
  
  0.955
CV_3789
Probable glycerate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1052; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
 0.923
CV_1724
Probable phosphoglycerate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0111.
    
 0.917
CV_1402
Probable phosphoglycolate phosphatase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0546.
  
  
 
0.907
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
      0.644
CV_2181
Probable dehydrogenase/reductase oxireductase protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1028; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.610
CV_1394
Probable beta-phosphoglucomutase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0637.
 
  
 0.567
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
       0.548
moaA2
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
    0.505
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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