STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fabZ(3R)-hydroxymyristol acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (150 aa)    
Predicted Functional Partners:
lpxA
acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
  
 0.998
lpxD
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase (firA protein); Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
  
 0.997
fabD
Malonyl CoA-acyl carrier protein transacylase; Identified by sequence similarity; putative; ORF located using Blastx/COG0331.
 
  
 0.983
fabI
Enoyl-[acyl-carrier-protein] reductase (NADH); Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0623.
 
 
 0.982
fabF
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
  
 0.977
CV_3950
Probable (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0764.
  
  
  0.972
fabG1
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.968
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
 
 
 0.967
CV_3743
Probable enoyl-[acyl-carrier-protein] reductase (NADH); Identified by sequence similarity; putative; ORF located using Blastx/COG0623.
 
 
 0.966
CV_1546
Probable 3-oxoacyl-[acyl-carrier protein] reductase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1028.
 
 
 0.960
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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