STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CV_2297Probable outer membrane lipoprotein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1464; Belongs to the nlpA lipoprotein family. (269 aa)    
Predicted Functional Partners:
CV_2295
Probable ABC transporter system, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
 
 0.999
CV_2296
Probable transmembrane ABC transporter protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2011.
 0.999
metY
O-acetylhomoserine (thiol)-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2873.
  
    0.807
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.595
metF
5,10-methylenetetrahydrofolate reductase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0685; Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.585
CV_0203
Probable 5-methyltetrahydrofolate-homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
  
 0.567
metE
5-methyltetrahydropteroyltriglutamate- homocysteine S-methyl; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
  
 0.538
CV_1275
Probable ABC transporter, periplasmic-binding protein; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG0834/TC:3.A.1.3.10; Belongs to the bacterial solute-binding protein 3 family.
 
  
 0.531
sbp
Sulfate transport system sulfate-binding protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1613/TC:3.A.1.6.1.
  
  
 0.509
cysD
Sulfate adenylyltransferase subunit 2; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0175.
   
  
 0.497
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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