Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CV_2363Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG1956. (179 aa)    
Predicted Functional Partners:
tyrB2
Aromatic-amino-acid transaminase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1448.
    
  0.906
tyrB1
Aromatic-amino-acid transaminase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1448.
    
  0.906
metY
O-acetylhomoserine (thiol)-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2873.
    
  0.901
CV_0203
Probable 5-methyltetrahydrofolate-homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.900
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
  0.900
CV_2004
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1956.
     
  0.900
metE
5-methyltetrahydropteroyltriglutamate- homocysteine S-methyl; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
     
  0.900
msrA
protein-methionine-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
    
 0.757
CV_0875
Probable carbonic anhydrase, family 3; Identified by sequence similarity; putative; ORF located using Blastx/COG0663.
      0.684
CV_2097
Probable nitrilase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0388.
 
      0.614
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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