Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CV_2385Probable integral membrane protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0668. (281 aa)    
Predicted Functional Partners:
prfC
Peptide chain release factor RF-3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
       0.783
gcvP
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
    0.710
CV_3398
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1241.
  
     0.655
CV_2384
Probable transcriptional regulator, TetR family; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1309.
       0.586
ribAB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
  
    0.546
kefB
Glutathione-regulated potassium-efflux system protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1226/TC:2.A.37.1.2; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
  
 0.492
CV_3617
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0810/TC:3.D.3.1.1.
  
     0.491
CV_4069
Probable cytochrome c5; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3245.
  
   
 0.480
ribE
Riboflavin synthase, alpha chain; Identified by sequence similarity; putative; ORF located using Blastx/COG0307.
       0.479
CV_2388
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2102.
       0.469
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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