STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acnBAconitate hydratase; Identified by sequence similarity; putative; ORF located using Blastx/COG1049; Belongs to the aconitase/IPM isomerase family. (862 aa)    
Predicted Functional Partners:
gtlA
Citrate (si)-synthase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0372; Belongs to the citrate synthase family.
  
 
 0.986
CV_3664
Probable isocitrate dehydrogenase (NADP); Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2838; Belongs to the monomeric-type IDH family.
  
 
 0.949
acnA1
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
    
 0.941
prpC
Citrate synthase 2; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0372; Belongs to the citrate synthase family.
  
 
 0.930
CV_2053
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2828.
 
  
 0.928
CV_2031
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2828.
 
  
 0.926
prpB
Carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
    
 0.926
aceA
Isocitrate lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2224.
     
 0.919
fumA
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.907
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
  
 0.895
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.