Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CV_2565Probable oxidoreductase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1028; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (240 aa)    
Predicted Functional Partners:
entF
Enterobactin synthetase component F; Identified by sequence similarity; putative; ORF located using Blastx/COG1020.
 
    0.912
CV_3953
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0451.
      0.908
hetM
Polyketide synthase; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG3320.
      0.908
tpx
Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
   
    0.682
entE
2,3-dihydroxybenzoate-AMP ligase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1021/TC:9.B.17.1.4.
      0.677
flaG
Flagellin protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1334.
    
   0.655
tag
DNA-3-methyladenine glycosylase I; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2818.
      0.638
gcvP
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
      0.619
CV_2566
Probable peroxide-inducible genes activator; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0583; Belongs to the LysR transcriptional regulatory family.
 
   
 0.593
CV_2177
Probable dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1028.
 
  
 0.562
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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