Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CV_2636Probable thiol:disulfide interchange protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0526/TC:5.A.1.1.1. (370 aa)    
Predicted Functional Partners:
dsbG
Thiol:disulfide interchange protein DsbG; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
  
 
 0.893
dsbE
Thioredoxin-related transmembrane protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0526.
  
 
 0.879
dsbC
Protein disulfide-isomerase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
  
 
 0.820
CV_1895
Probable thioredoxin-disulfide reductase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0526.
  
 
 0.818
dsbD
Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
  
     0.774
trh1
Transcriptional regulator; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0229; Belongs to the MsrB Met sulfoxide reductase family.
   
 
 0.773
msrA
protein-methionine-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 
 0.771
armS
Two-component sensor kinase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0642.
 
    0.757
CV_2635
Probable two-component response regulator; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0745.
 
     0.607
dsbA
Thiol:disulfide interchange protein dsbA precursor; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0526.
  
 
 0.578
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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