STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsdAD-serine dehydratase; Identified by sequence similarity; putative; ORF located using Blastx/COG3048; Belongs to the serine/threonine dehydratase family. DsdA subfamily. (448 aa)    
Predicted Functional Partners:
sdaA2
L-serine dehydratase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.918
sdaA1
L-serine dehydratase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.918
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
     
 0.910
tdcB
Threonine dehydratase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1171.
     
 0.910
pth
aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
 
      0.857
gloA
Lactoylglutathione lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0346.
     
  0.800
CV_1724
Probable phosphoglycerate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0111.
     
  0.800
CV_2020
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0346.
     
  0.800
dsdC
D-serine deaminase activator; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0583; Belongs to the LysR transcriptional regulatory family.
       0.773
CV_0875
Probable carbonic anhydrase, family 3; Identified by sequence similarity; putative; ORF located using Blastx/COG0663.
 
      0.685
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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