Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CV_2703Probable outer membrane protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1538/TC:1.B.17.3.1. (455 aa)    
Predicted Functional Partners:
macB
Probable ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 0.968
CV_2705
Probable membrane protein; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG0845/TC:8.A.1.2.1; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.944
CV_2240
Probable multidrug efflux protein; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG0845/TC:8.A.1.6.1; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.825
CV_0435
Probable multidrug efflux membrane permease; Identified by sequence similarity; putative; ORF located using Blastx/COG0845/TC:8.A.1.6.1; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.815
acrB
Acriflavin resistance protein B; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0841/TC:2.A.6.2.2.
 
 0.784
acrD
Acriflavin resistance protein D; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0841/TC:2.A.6.2.7.
 
 0.745
CV_2732
Probable membrane protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0845/TC:8.A.1.6.1; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.673
emrA
Multidrug resistance secretion protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1566/TC:8.A.1.1.1.
 
 
 0.632
CV_0709
Probable multidrug resistance transmembrane protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1566/TC:8.A.1.1.1.
 
 
 0.620
CV_2460
Probable membrane protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0845/TC:8.A.1.1.1.
 
 
 0.587
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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