Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
phaCPolyhydroxyalkanoate synthase; Involved in the production of polyhydroxyalkonic acids (PHAs), composed primarily of 3-hydroxybutyric acid (3HB) and 3- hydroxyvaleric acid (3HV). (568 aa)    
Predicted Functional Partners:
phaB
acetoacetyl-CoA reductase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1028.
  
 
 0.987
CV_3819
Probable maoC-like dehydratase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2030.
 
  
 0.947
phaA
acetyl-CoA C-acetyltransferase; Involved in the production of polyhydroxyalkonic acids (PHAs), composed primarily of 3-hydroxybutyric acid (3HB) and 3- hydroxyvaleric acid (3HV); Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 0.865
ptb
Phosphate acetyltransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0280.
  
 0.851
phbF
PhbF protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx.
 
   
 0.831
fadB
3-hydroxyacyl-CoA dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1024.
      
 0.721
CV_2843
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1752.
 
   
 0.701
phaJ
Phenylacetic acid permease; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0591/TC:2.A.21.7.1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
      
 0.646
ackA-2
Probable member of the acetate kinase family; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
 
  
 0.604
fadA
acetyl-CoA C-acyltransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0183; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 0.581
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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