Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
phaAacetyl-CoA C-acetyltransferase; Involved in the production of polyhydroxyalkonic acids (PHAs), composed primarily of 3-hydroxybutyric acid (3HB) and 3- hydroxyvaleric acid (3HV); Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)    
Predicted Functional Partners:
fadB
3-hydroxyacyl-CoA dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1024.
  
 0.999
paaH
3-hydroxybutyryl-CoA dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1250.
 0.998
phaB
acetoacetyl-CoA reductase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1028.
  
 0.973
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.955
CV_2723
Probable acyl-CoA dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1960.
  
 0.955
mvaB
hydroxymethylglutaryl-CoA lyase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0119/TC:3.B.1.1.1.
  
 
 0.941
gtlA
Citrate (si)-synthase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0372; Belongs to the citrate synthase family.
  
 0.939
adhE
Acetaldehyde dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1454; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
   
 0.939
prpC
Citrate synthase 2; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0372; Belongs to the citrate synthase family.
  
 0.939
aceF
Dihydrolipoamide S-acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.938
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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