Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CV_2828Hypothetical protein. (250 aa)    
Predicted Functional Partners:
CV_3767
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2104.
  
 
 0.928
thiG
Thiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
  
 0.884
moaE
Molybdopterin converting factor subunit 2; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0314.
  
 0.877
moaD
Molybdopterin-converting factor subunit 1; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1977.
  
 
 0.809
thiC
Thiamin biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.804
nifS
Pyridoxal-phosphate-dependent aminotransferase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
   
 0.793
thiD
Hydroxymethylpyrimidine kinase; Identified by sequence similarity; putative; ORF located using Blastx/COG0351.
  
  
 0.777
trxB
Thioredoxin reductase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0492.
  
    0.689
CV_3611
Probable bifunctional dGTP-pyrophosphohydrolase/thiamine phosphate synthase; Identified by sequence similarity; putative; ORF located using Blastx/COG0494; Belongs to the Nudix hydrolase family.
  
 
 0.656
thiE
Probable thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.607
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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