node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CV_3912 | dbpA | CV_3912 | CV_2853 | Conserved hypothetical protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | ATP-dependent RNA helicase dbpA; Identified by sequence similarity; putative; ORF located using Blastx/COG0513; Belongs to the DEAD box helicase family. | 0.861 |
CV_3912 | pnp | CV_3912 | CV_1466 | Conserved hypothetical protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.543 |
CV_3912 | rplC | CV_3912 | CV_4186 | Conserved hypothetical protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.956 |
CV_3912 | rplD | CV_3912 | CV_4185 | Conserved hypothetical protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.929 |
CV_3912 | rplJ | CV_3912 | CV_4195 | Conserved hypothetical protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.964 |
CV_3912 | rplM | CV_3912 | CV_3697 | Conserved hypothetical protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.943 |
CV_3912 | rplX | CV_3912 | CV_4175 | Conserved hypothetical protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.943 |
dbpA | CV_3912 | CV_2853 | CV_3912 | ATP-dependent RNA helicase dbpA; Identified by sequence similarity; putative; ORF located using Blastx/COG0513; Belongs to the DEAD box helicase family. | Conserved hypothetical protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.861 |
dbpA | fusA | CV_2853 | CV_4189 | ATP-dependent RNA helicase dbpA; Identified by sequence similarity; putative; ORF located using Blastx/COG0513; Belongs to the DEAD box helicase family. | Elongation factor; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | 0.864 |
dbpA | hrpA | CV_2853 | CV_1516 | ATP-dependent RNA helicase dbpA; Identified by sequence similarity; putative; ORF located using Blastx/COG0513; Belongs to the DEAD box helicase family. | ATP-dependent helicase hrpA; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1643. | 0.821 |
dbpA | nnrE | CV_2853 | CV_3338 | ATP-dependent RNA helicase dbpA; Identified by sequence similarity; putative; ORF located using Blastx/COG0513; Belongs to the DEAD box helicase family. | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.864 |
dbpA | pnp | CV_2853 | CV_1466 | ATP-dependent RNA helicase dbpA; Identified by sequence similarity; putative; ORF located using Blastx/COG0513; Belongs to the DEAD box helicase family. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.910 |
dbpA | rplC | CV_2853 | CV_4186 | ATP-dependent RNA helicase dbpA; Identified by sequence similarity; putative; ORF located using Blastx/COG0513; Belongs to the DEAD box helicase family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.858 |
dbpA | rplD | CV_2853 | CV_4185 | ATP-dependent RNA helicase dbpA; Identified by sequence similarity; putative; ORF located using Blastx/COG0513; Belongs to the DEAD box helicase family. | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.847 |
dbpA | rplJ | CV_2853 | CV_4195 | ATP-dependent RNA helicase dbpA; Identified by sequence similarity; putative; ORF located using Blastx/COG0513; Belongs to the DEAD box helicase family. | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.787 |
dbpA | rplM | CV_2853 | CV_3697 | ATP-dependent RNA helicase dbpA; Identified by sequence similarity; putative; ORF located using Blastx/COG0513; Belongs to the DEAD box helicase family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.812 |
dbpA | rplX | CV_2853 | CV_4175 | ATP-dependent RNA helicase dbpA; Identified by sequence similarity; putative; ORF located using Blastx/COG0513; Belongs to the DEAD box helicase family. | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.784 |
fusA | dbpA | CV_4189 | CV_2853 | Elongation factor; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | ATP-dependent RNA helicase dbpA; Identified by sequence similarity; putative; ORF located using Blastx/COG0513; Belongs to the DEAD box helicase family. | 0.864 |
fusA | hrpA | CV_4189 | CV_1516 | Elongation factor; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | ATP-dependent helicase hrpA; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1643. | 0.859 |
fusA | pnp | CV_4189 | CV_1466 | Elongation factor; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.888 |