STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
holCDNA polymerase III, chi subunit; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2927. (141 aa)    
Predicted Functional Partners:
holA
DNA-directed DNA polymerase, delta subunit; Identified by sequence similarity; putative; ORF located using Blastx/COG1466.
  
 
 0.998
holB
DNA-directed DNA polymerase III, delta subunit; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0470.
  
 
 0.998
dnaE
DNA-directed DNA polymerase III, alpha subunit; Identified by sequence similarity; putative; ORF located using Blastx.
   
 0.995
dnaX
DNA polymerase subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
 0.995
dnaN
DNA-directed DNA polymerase, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for init [...]
    
 0.980
ssb
Single-strand DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
    
 
 0.947
dnaQ
DNA-directed DNA polymerase, epsilon chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
   
 0.935
CV_2751
Probable exonuclease; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0847.
   
 0.935
CV_1020
Probable DNA-directed DNA polymerase III (epsilon subunit); Identified by sequence similarity; putative; ORF located using Blastx/COG0847.
   
 0.930
CV_2946
Probable DNA polymerase III; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0847.
   
 0.925
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.