STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lolCLipoprotein releasing system trasmembrane protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0577/TC:3.A.1.125.1. (412 aa)    
Predicted Functional Partners:
lolD
Probable ATP-binding component, ABC transporter; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
 0.998
lolA
Outer membrane lipoproteins carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
 
 
 
 0.959
macB
Probable ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.894
lolB
Probable outer membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
    
 
 0.871
CV_3734
Probable ATP-binding component, ABC transporter; Identified by sequence similarity; putative; ORF located using Blastx/COG1136.
  
 
 0.855
CV_3943
Probable ATP-binding component of ABC transporter; Identified by sequence similarity; putative; ORF located using Blastx/COG1136.
  
 
 0.843
CV_4397
Probable ABC transporter, ATP-binding protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1136.
  
 
 0.843
bamA
Probable outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
   
 0.802
CV_2965
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx.
       0.760
CV_3941
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx.
   
 
 0.752
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.