STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CV_3012Probable serine carboxypeptidase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx. (418 aa)    
Predicted Functional Partners:
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
    
   0.682
caiB
Carnitine dehydratase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1804; Belongs to the CoA-transferase III family.
       0.578
CV_0043
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0790.
  
 
 
 0.547
CV_3157
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1881.
   
 
 0.520
CV_3009
Probable sensor/response regulator hybrid; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0642.
 
     0.496
flaD
Flagellin D; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
       0.485
dnaK
Heat shock protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 
 0.471
CV_3014
Probable transmembrane transport protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0477.
   
 
 0.459
secY
Preprotein translocase secY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
 
 0.416
CV_2717
Probable extracellular serine protease; Identified by sequence similarity; putative; ORF located using Blastx/COG1404; Belongs to the peptidase S8 family.
   
 
 0.413
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.