Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rfaEADP-heptose synthase; Identified by sequence similarity; putative; ORF located using Blastx. (291 aa)    
Predicted Functional Partners:
CV_0485
Probable transferase protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
   
 0.982
CV_1657
Probable histidinol-phosphatase; Identified by sequence similarity; putative; ORF located using Blastx.
 
  
 0.982
gmhA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
  
 0.981
lpcA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
  
 0.980
rfaD
ADP-L-glycero-D-mannoheptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
 
  
 0.970
rfaC
Lipopolysaccharide heptosyltransferase I; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0859.
 
   
 0.930
rfaQ
Lipopolysaccharide glucosyltransferase I; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0859.
 
   
 0.929
rfaF
ADP-heptose--LPS heptosyltransferase II; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0859.
   
 0.844
CV_3039
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx.
       0.701
rfaB
Lipopolysaccharide glucosyltransferase I; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0438.
 
   
 0.695
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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