Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CV_3055Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2072. (625 aa)    
Predicted Functional Partners:
speE
Conserved hypothetical protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
 
  0.906
CV_2025
Probable aminotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0161.
    
  0.902
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
  
 0.861
hemH
Ferrochelatase, protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
 
 0.846
CV_3056
Probable cytochrome c precursor; Identified by sequence similarity; putative; ORF located using Blastx/COG2010.
 
     0.833
comF
Competence protein F; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1040.
  
    0.733
CV_1570
Probable chelatase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1239.
  
  
 0.525
hemB
Porphobilinogen synthase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0113; Belongs to the ALAD family.
  
  
 0.470
cobA2
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
     
 0.447
fruA
protein-N p-phosphohistidine-sugar phosphotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1445/TC:4.A.2.1.1.
       0.443
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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