Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pepPxaa-Pro aminopeptidase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0006; Belongs to the peptidase M24B family. (431 aa)    
Predicted Functional Partners:
ubiH
2-octaprenyl-6-methoxyphenol hydroxylase oxidoreductase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0654.
 
  
 0.828
visC
Oxidoreductase protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0654.
  
  
 0.803
dsbC
Protein disulfide-isomerase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
     
 0.732
folD
Methylenetetrahydrofolate dehydrogenase/cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.667
CV_3118
Hypothetical protein.
       0.645
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
    0.537
CV_3123
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx.
     
 0.537
pepD
Aminoacyl-histidine dipeptidase precursor; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2195.
  
 
 0.492
nudJ
Probable MutT-like protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0494; Belongs to the Nudix hydrolase family. NudJ subfamily.
 
   
 0.485
CV_3024
Probable glutathione S-transferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0625.
  
   
 0.476
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
Server load: medium (54%) [HD]