Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pgmPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (507 aa)    
Predicted Functional Partners:
pgk
Phosphoglycerate kinase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0126; Belongs to the phosphoglycerate kinase family.
  
 
 0.988
eno
Phosphopyruvate hydratase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0148.
 
 
 0.956
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.944
gpmB
Phosphoglycerate mutase 2; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0406; Belongs to the phosphoglycerate mutase family.
     
 0.917
ttuD
Hydroxypyruvate reductase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2379.
    
  0.905
pgi2
Glucose-6-phosphate isomerase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0166.
  
 
 0.901
pgi1
Glucose-6-phosphate isomerase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0166.
  
 
 0.901
agaY
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
   
 
 0.886
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
   
 
 0.869
tktA
Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.866
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
Server load: medium (46%) [HD]