Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
dcuBAnaerobic C4-dicarboxylate membrane transporter protein; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. (442 aa)    
Predicted Functional Partners:
frdC
Fumarate reductase, subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane; Belongs to the FrdC family.
 
  
 0.877
frdD
Fumarate reductase, subunit D; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane; Belongs to the FrdD family.
 
    0.870
frdA
Fumarate reductase flavoprotein subunit; Identified by sequence similarity; putative; ORF located using Blastx/COG1053.
 
  
 0.809
frdB
Fumarate reductase, subunit B; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0479.
 
    0.808
maeN
Na+/malate symporter; Identified by sequence similarity; putative; ORF located using Blastx/COG3493/TC:2.A.24.2.3.
      
 0.681
dctA
C4-dicarboxylic acids transport protein (Na+/H+ dicarboxylate symporter); Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
   
  
 0.676
narP
Nitrate/nitrite response regulator protein; Identified by sequence similarity; putative; ORF located using Blastx/COG2197.
      
 0.645
fumA
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.543
sdaC
Serine transporter; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0814/TC:2.A.42.2.1.
  
  
 0.503
nrdD
Ribonucleoside-triphosphate reductase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1328.
     
 0.426
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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