| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CV_0203 | CV_3394 | CV_0203 | CV_3394 | Probable 5-methyltetrahydrofolate-homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Probable cystathionine gamma-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0626. | 0.972 |
| CV_0203 | CV_3597 | CV_0203 | CV_3597 | Probable 5-methyltetrahydrofolate-homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Probable cysteine synthase B; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0031. | 0.876 |
| CV_0203 | cysB2 | CV_0203 | CV_3395 | Probable 5-methyltetrahydrofolate-homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0517. | 0.944 |
| CV_0203 | cysK | CV_0203 | CV_3561 | Probable 5-methyltetrahydrofolate-homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cysteine synthase; Identified by sequence similarity; putative; ORF located using Blastx/COG0031; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.876 |
| CV_0203 | ilvE | CV_0203 | CV_2094 | Probable 5-methyltetrahydrofolate-homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Branched-chain-amino-acid transaminase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.475 |
| CV_0203 | metE | CV_0203 | CV_3604 | Probable 5-methyltetrahydrofolate-homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyl; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.985 |
| CV_0203 | metG | CV_0203 | CV_1206 | Probable 5-methyltetrahydrofolate-homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.932 |
| CV_3182 | CV_3394 | CV_3182 | CV_3394 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3690. | Probable cystathionine gamma-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0626. | 0.900 |
| CV_3182 | CV_3597 | CV_3182 | CV_3597 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3690. | Probable cysteine synthase B; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0031. | 0.900 |
| CV_3182 | cysK | CV_3182 | CV_3561 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3690. | Cysteine synthase; Identified by sequence similarity; putative; ORF located using Blastx/COG0031; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.900 |
| CV_3394 | CV_0203 | CV_3394 | CV_0203 | Probable cystathionine gamma-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0626. | Probable 5-methyltetrahydrofolate-homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.972 |
| CV_3394 | CV_3182 | CV_3394 | CV_3182 | Probable cystathionine gamma-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0626. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3690. | 0.900 |
| CV_3394 | CV_3597 | CV_3394 | CV_3597 | Probable cystathionine gamma-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0626. | Probable cysteine synthase B; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0031. | 0.964 |
| CV_3394 | cysB2 | CV_3394 | CV_3395 | Probable cystathionine gamma-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0626. | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0517. | 0.999 |
| CV_3394 | cysK | CV_3394 | CV_3561 | Probable cystathionine gamma-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0626. | Cysteine synthase; Identified by sequence similarity; putative; ORF located using Blastx/COG0031; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.960 |
| CV_3394 | ilvE | CV_3394 | CV_2094 | Probable cystathionine gamma-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0626. | Branched-chain-amino-acid transaminase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.918 |
| CV_3394 | metE | CV_3394 | CV_3604 | Probable cystathionine gamma-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0626. | 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyl; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.957 |
| CV_3394 | metG | CV_3394 | CV_1206 | Probable cystathionine gamma-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0626. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.921 |
| CV_3394 | sseA | CV_3394 | CV_4245 | Probable cystathionine gamma-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0626. | Thiosulfate sulfurtransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2897. | 0.931 |
| CV_3394 | trxB | CV_3394 | CV_2813 | Probable cystathionine gamma-lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0626. | Thioredoxin reductase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0492. | 0.907 |