STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CV_3407Probable prephenate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/COG0287. (296 aa)    
Predicted Functional Partners:
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
  
 0.983
hisC
Histidinol-phosphate aminotransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0079; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.981
CV_0038
Probable histidinol-phosphate aminotransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0079.
  
 
 0.980
pheA
Chorismate mutase/prephenate dehydratase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1605.
 
 0.978
tyrB2
Aromatic-amino-acid transaminase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1448.
    
 0.923
tyrB1
Aromatic-amino-acid transaminase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1448.
    
 0.923
cmk
Cytidylate kinase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0283.
 
  
 0.917
CV_0224
Probable carboxycyclohexadienyl dehydratase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0834/TC:3.A.1.3.10.
    
 0.906
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
  
 0.873
CV_3406
Probable oxidoreductase; Identified by sequence similarity; putative; ORF located using Blastx/COG1028.
    
 0.840
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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