STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pncBNicotinic acid phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (402 aa)    
Predicted Functional Partners:
pncA
Bifunctional pyrazinamidase/nicotinamidase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1335.
 
 
 0.982
nadC
Nicotinate-nucleotide pyrophosphorylase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0157; Belongs to the NadC/ModD family.
   
 0.951
nadD
Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.934
cinA
cinA-related protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1546; Belongs to the CinA family.
  
 
 0.927
nudC
Probable NAD diphosphatase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2816.
    
 0.925
deoD
Purine nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0813.
     
 0.917
ushA
UDP-sugar diphosphatase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0737; Belongs to the 5'-nucleotidase family.
    
 0.902
CV_3083
Probable UDP-sugar diphosphatase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0737; Belongs to the 5'-nucleotidase family.
    
 0.902
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.901
CV_3420
Conserved hypothetical protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.
 
     0.780
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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