| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CV_1601 | CV_3572 | CV_1601 | CV_3572 | Probable transmembrane protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0730. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | 0.510 |
| CV_1601 | cobA2 | CV_1601 | CV_0813 | Probable transmembrane protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0730. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.442 |
| CV_1601 | cysH | CV_1601 | CV_3574 | Probable transmembrane protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0730. | Phosphoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. | 0.434 |
| CV_1601 | cysI | CV_1601 | CV_3573 | Probable transmembrane protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0730. | Sulfite reductase hemoprotein, beta subunit; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0155. | 0.520 |
| CV_3572 | CV_1601 | CV_3572 | CV_1601 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | Probable transmembrane protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0730. | 0.510 |
| CV_3572 | cobA2 | CV_3572 | CV_0813 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.498 |
| CV_3572 | cysA | CV_3572 | CV_1828 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | Sulfate transport ATP-binding ABC transporter protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | 0.575 |
| CV_3572 | cysB1 | CV_3572 | CV_3575 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | Transcriptional regulator CysB; Identified by sequence similarity; putative; ORF located using Blastx/COG0583; Belongs to the LysR transcriptional regulatory family. | 0.450 |
| CV_3572 | cysD | CV_3572 | CV_2306 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | Sulfate adenylyltransferase subunit 2; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0175. | 0.562 |
| CV_3572 | cysH | CV_3572 | CV_3574 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | Phosphoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. | 0.875 |
| CV_3572 | cysI | CV_3572 | CV_3573 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | Sulfite reductase hemoprotein, beta subunit; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0155. | 0.992 |
| CV_3572 | cysN | CV_3572 | CV_2307 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.543 |
| CV_3572 | cysU | CV_3572 | CV_1830 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | Sulfate transport system permease protein CysU; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. | 0.529 |
| CV_3572 | cysW | CV_3572 | CV_1829 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | Sulfate transport system permease protein CysW; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0555/TC:3.A.1.6.1. | 0.439 |
| cobA2 | CV_1601 | CV_0813 | CV_1601 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Probable transmembrane protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0730. | 0.442 |
| cobA2 | CV_3572 | CV_0813 | CV_3572 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | 0.498 |
| cobA2 | cysA | CV_0813 | CV_1828 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Sulfate transport ATP-binding ABC transporter protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. | 0.511 |
| cobA2 | cysD | CV_0813 | CV_2306 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Sulfate adenylyltransferase subunit 2; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0175. | 0.914 |
| cobA2 | cysH | CV_0813 | CV_3574 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Phosphoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. | 0.954 |
| cobA2 | cysI | CV_0813 | CV_3573 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Sulfite reductase hemoprotein, beta subunit; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0155. | 0.965 |