| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CV_3572 | cobA2 | CV_3572 | CV_0813 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.498 |
| CV_3572 | cysD | CV_3572 | CV_2306 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | Sulfate adenylyltransferase subunit 2; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0175. | 0.562 |
| CV_3572 | cysH | CV_3572 | CV_3574 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | Phosphoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. | 0.875 |
| CV_3572 | cysI | CV_3572 | CV_3573 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | Sulfite reductase hemoprotein, beta subunit; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0155. | 0.992 |
| CV_3572 | cysN | CV_3572 | CV_2307 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.543 |
| CV_3597 | cobA2 | CV_3597 | CV_0813 | Probable cysteine synthase B; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0031. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.510 |
| CV_3597 | cysC | CV_3597 | CV_2104 | Probable cysteine synthase B; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0031. | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.567 |
| CV_3597 | cysD | CV_3597 | CV_2306 | Probable cysteine synthase B; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0031. | Sulfate adenylyltransferase subunit 2; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0175. | 0.739 |
| CV_3597 | cysH | CV_3597 | CV_3574 | Probable cysteine synthase B; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0031. | Phosphoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. | 0.538 |
| CV_3597 | cysI | CV_3597 | CV_3573 | Probable cysteine synthase B; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0031. | Sulfite reductase hemoprotein, beta subunit; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0155. | 0.954 |
| CV_3597 | cysK | CV_3597 | CV_3561 | Probable cysteine synthase B; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0031. | Cysteine synthase; Identified by sequence similarity; putative; ORF located using Blastx/COG0031; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.926 |
| CV_3597 | cysN | CV_3597 | CV_2307 | Probable cysteine synthase B; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0031. | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.565 |
| CV_3597 | metZ | CV_3597 | CV_2725 | Probable cysteine synthase B; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0031. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.958 |
| CV_3597 | sseA | CV_3597 | CV_4245 | Probable cysteine synthase B; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0031. | Thiosulfate sulfurtransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2897. | 0.845 |
| cobA2 | CV_3572 | CV_0813 | CV_3572 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx. | 0.498 |
| cobA2 | CV_3597 | CV_0813 | CV_3597 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Probable cysteine synthase B; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0031. | 0.510 |
| cobA2 | cysC | CV_0813 | CV_2104 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.933 |
| cobA2 | cysD | CV_0813 | CV_2306 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Sulfate adenylyltransferase subunit 2; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0175. | 0.914 |
| cobA2 | cysH | CV_0813 | CV_3574 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Phosphoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. | 0.954 |
| cobA2 | cysI | CV_0813 | CV_3573 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Sulfite reductase hemoprotein, beta subunit; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0155. | 0.965 |