Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cysHPhosphoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. (234 aa)    
Predicted Functional Partners:
cysC
Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.
 
 0.999
cysI
Sulfite reductase hemoprotein, beta subunit; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0155.
 
 0.999
cysD
Sulfate adenylyltransferase subunit 2; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0175.
 
 0.998
cysN
Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
 0.997
cobA2
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
  
 0.954
cysQ
Inositol monophosphatase family protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1218.
  
 
 0.937
sseA
Thiosulfate sulfurtransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2897.
    
 0.932
cysA
Sulfate transport ATP-binding ABC transporter protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
  
  
 0.919
cysW
Sulfate transport system permease protein CysW; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0555/TC:3.A.1.6.1.
  
  
 0.906
tauD
Taurine dioxygenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2175.
     
 0.904
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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