Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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ubiA4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (490 aa)    
Predicted Functional Partners:
ubiX
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
 
  
 0.970
ubiD
Probable 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
 
  
 0.968
ispB
Octaprenyl-diphosphate synthase; Identified by sequence similarity; putative; ORF located using Blastx/COG0142; Belongs to the FPP/GGPP synthase family.
 
 
 0.888
ubiG
3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
 
 0.753
visC
Oxidoreductase protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0654.
  
   
 0.751
ubiF
Monooxygenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0654.
  
   
 0.743
ubiH
2-octaprenyl-6-methoxyphenol hydroxylase oxidoreductase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0654.
  
   
 0.741
CV_1570
Probable chelatase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1239.
  
  
 0.721
CV_3916
Probable electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone.
 
  
 0.672
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
    0.651
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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