Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CV_3764Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1610. (148 aa)    
Predicted Functional Partners:
rpsU
30S ribosomal protein S21; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0828; Belongs to the bacterial ribosomal protein bS21 family.
  
  
 0.953
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
    0.779
rpsO
30s ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
  
    0.744
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
    0.606
rpmE
50S ribosomal protein L31; Binds the 23S rRNA.
   
    0.591
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
    0.493
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
    0.473
rpmB
50S ribosomal protein L28; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0227; Belongs to the bacterial ribosomal protein bL28 family.
  
    0.466
rpmF
50S ribosomal protein L32; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0333; Belongs to the bacterial ribosomal protein bL32 family.
  
    0.427
argS
arginyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0018.
  
    0.425
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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