Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (193 aa)    
Predicted Functional Partners:
purB
Adenylosuccinate lyase; Identified by sequence similarity; putative; ORF located using Blastx/COG0015; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.987
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0138.
  
 0.968
CV_4278
Probable ribokinase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0524.
  
 0.950
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.944
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.933
deoD
Purine nucleoside phosphorylase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0813.
    
 0.929
ushA
UDP-sugar diphosphatase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0737; Belongs to the 5'-nucleotidase family.
    
 0.922
CV_3083
Probable UDP-sugar diphosphatase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0737; Belongs to the 5'-nucleotidase family.
    
 0.922
CV_2191
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1496; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.910
icc
3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
    
  0.901
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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