Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
trmBProbable S-adenosylmethionine-dependent methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (226 aa)    
Predicted Functional Partners:
hemK
HemK protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
 
 
 
 0.897
truB
tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 
 0.842
CV_4262
Probable sun-like protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
 
 0.811
CV_3618
Probable sun-like protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0144.
   
 
 0.784
rpmD
50S ribosomal protein L30; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1841.
   
  
 0.730
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
   
 
 0.703
CV_0373
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1432.
  
  
 0.673
CV_0746
Hypothetical protein.
  
  
 0.673
truA
Pseudouridylate synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
 
 0.654
CV_3785
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0451.
       0.652
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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