Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CV_3789Probable glycerate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1052; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa)    
Predicted Functional Partners:
ttuD
Hydroxypyruvate reductase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2379.
 
 0.950
CV_1724
Probable phosphoglycerate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0111.
 
  
0.931
CV_3870
Probable oxidoreductase protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2084.
 
  
 0.929
aceB
Malate synthase A; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2225; Belongs to the malate synthase family.
  
 
 0.927
gph
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
 
  
 0.923
aceA
Isocitrate lyase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2224.
     
 0.921
eda
2-dehydro-3-deoxy-phosphogluconate aldolase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0800.
    
  0.911
CV_1402
Probable phosphoglycolate phosphatase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0546.
    
  0.906
CV_1817
Probable phosphoglycolate phosphatase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0546.
    
  0.906
CV_3790
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0477.
       0.768
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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