Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fdoHFormate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0437/TC:5.A.3.2.1. (295 aa)    
Predicted Functional Partners:
fdnG
Formate dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0243/TC:5.A.3.2.1.
 0.999
fdoI
Formate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2864/TC:5.A.3.2.1.
 
 0.999
fdhE
Formate dehydrogenase formation protein FdhE; Identified by sequence similarity; putative; ORF located using Blastx/COG3058.
  
 0.951
CV_1622
Probable formate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/COG0243; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.920
napA
Nitrate reductase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0243/TC:5.A.3.2.1; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
  
 
 0.920
CV_0739
Probable esterase; Serine hydrolase involved in the detoxification of formaldehyde.
     
  0.900
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
     
  0.900
hcnA
Hydrogen cyanide synthase HcnA; Identified by sequence similarity; putative; ORF located using Blastx/COG0446.
  
  
 0.869
maeB
NADP-dependent malate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0281.
 
  
 0.865
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.843
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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