| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CV_1322 | CV_3387 | CV_1322 | CV_3387 | Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.997 |
| CV_1322 | smc | CV_1322 | CV_3908 | Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | Probable chromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.950 |
| CV_3387 | CV_1322 | CV_3387 | CV_1322 | Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.997 |
| CV_3387 | smc | CV_3387 | CV_3908 | Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | Probable chromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.846 |
| CV_3387 | topA | CV_3387 | CV_4269 | Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.856 |
| CV_3909 | CV_3911 | CV_3909 | CV_3911 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1678; Belongs to the UPF0301 (AlgH) family. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx. | 0.781 |
| CV_3909 | smc | CV_3909 | CV_3908 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1678; Belongs to the UPF0301 (AlgH) family. | Probable chromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.652 |
| CV_3911 | CV_3909 | CV_3911 | CV_3909 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1678; Belongs to the UPF0301 (AlgH) family. | 0.781 |
| CV_3911 | ffh | CV_3911 | CV_3833 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | 0.468 |
| CV_3911 | smc | CV_3911 | CV_3908 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx. | Probable chromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.598 |
| CV_4240 | smc | CV_4240 | CV_3908 | Probable chitinase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG3325; Belongs to the glycosyl hydrolase 18 family. | Probable chromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.835 |
| ffh | CV_3911 | CV_3833 | CV_3911 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx. | 0.468 |
| ffh | smc | CV_3833 | CV_3908 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | Probable chromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.573 |
| ffh | topA | CV_3833 | CV_4269 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.531 |
| gyrB | recQ | CV_0003 | CV_0477 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | ATP-dependent DNA helicase recQ; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0514. | 0.733 |
| gyrB | smc | CV_0003 | CV_3908 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Probable chromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.567 |
| gyrB | topA | CV_0003 | CV_4269 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.466 |
| parE | recQ | CV_1113 | CV_0477 | Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | ATP-dependent DNA helicase recQ; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0514. | 0.733 |
| parE | smc | CV_1113 | CV_3908 | Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | Probable chromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.567 |
| parE | topA | CV_1113 | CV_4269 | Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.462 |