STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CV_3944Probable 3-hydroxyisobutyrate dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2084. (296 aa)    
Predicted Functional Partners:
mmsB
3-hydroxyisobutyrate dehydrogenase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2084; Belongs to the HIBADH-related family.
  
  
 
0.925
mmsA1
Methylmalonate-semialdehyde dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1012.
 
 
 0.925
mmsA2
Methylmalonate-semialdehyde dehydrogenase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1012.
  
 
 0.910
CV_1436
Probable b-alanine-pyruvate transaminase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0161; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
prpC
Citrate synthase 2; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0372; Belongs to the citrate synthase family.
  
 
 0.821
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.819
ptb
Phosphate acetyltransferase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0280.
     
 0.801
pflB
Formate C-acetyltransferase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1882.
     
  0.800
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.800
FadH
2,4-dienoyl-CoA reductase; Identified by sequence similarity; putative; ORF located using Blastx/COG0446.
  
    0.785
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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