Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cyoEFarnesyl-diphosphate farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (302 aa)    
Predicted Functional Partners:
cyoA
Cytochrome o ubiquinol oxidase, subunit II; Identified by sequence similarity; putative; ORF located using Blastx/COG1622/TC:3.D.4.5.1.
 
  
 0.996
cyoD
Cytochrome o ubiquinol oxidase subunit IV; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG3125/TC:3.D.4.5.1.
 
  
 0.991
cyoC
Cytochrome o ubiquinol oxidase, subunit III; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1845/TC:3.D.4.5.1.
 
  
 0.989
cyoB
Cytochrome o ubiquinol oxidase, subunit I; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0843/TC:3.D.4.5.1; Belongs to the heme-copper respiratory oxidase family.
 
 
 0.988
ctaA
Cytochrome aa3 oxidase assembly protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1612.
  
 0.986
ctaG
Cytochrome C oxidase assembly transmembrane protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3175.
  
 0.984
coxA
Cytochrome-c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
 
 
 0.944
hemH
Ferrochelatase, protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
     
 0.921
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
  
  
 
0.920
CV_1964
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0748.
     
  0.900
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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