Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CV_4000Probable competence protein ComM; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0606. (500 aa)    
Predicted Functional Partners:
smf
Smf protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0758.
 
 0.942
comF
Competence protein F; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1040.
 
  
 0.883
CV_4001
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2960.
       0.808
CV_0654
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0792; Belongs to the UPF0102 family.
 
  
 0.778
def
Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
     0.776
comA
Competence protein; Identified by sequence similarity; putative; ORF located using Blastx/COG2333.
 
  
 0.683
CV_3999
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG3087.
       0.618
ruvC
Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
 
   
 0.588
dsbA
Thiol:disulfide interchange protein dsbA precursor; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0526.
       0.517
recG
ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
  
   
 0.477
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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