Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cviIN-acyl homoserine synthase; Identified by sequence similarity; putative; ORF located using Blastx/COG3916. (217 aa)    
Predicted Functional Partners:
cviR
Transcriptional activator, LuxR/UhpA family of regulators; Identified by sequence similarity; putative; ORF located using Blastx/COG2771.
 
 
 0.977
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
 0.910
mtaD
Probable atrazine chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
     
  0.900
mtnP
Probable 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
     
  0.900
CV_2191
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1496; Belongs to the multicopper oxidase YfiH/RL5 family.
     
  0.900
speE
Conserved hypothetical protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
     
  0.900
lasB
Class 4 metalloprotease; Extracellular zinc metalloprotease.
  
  
 0.778
CV_2001
Probable microbial collagenase; Identified by sequence similarity; putative; ORF located using Blastx.
  
     0.743
CV_0578
Probable guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
  
   
 0.671
vioA
vioA - tryptophan 2-monooxygenase; The enzyme generates the imine form of indole 3-pyruvate (IPA) from L-tryptophan (L-Trp), with concomitant two-electron reduction of O(2) to H(2)O(2).
      
 0.643
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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